No medicine cabinet or first aid kit is complete without Medline Instant Cold Packs. Cold therapy is essential within the first 48 hours after sustaining injuries to reduce pain and inflammation caused by strains and sprains as well as treat minor bumps bruises and muscle aches. They re even fantastic for treating headaches migraines and toothaches. Unfortunately injuries tooth pain and headaches can happen anywhere making immediate treatment challenging at best and impossible at worst. Medline instant ice packs don t need to be in the freezer so they can be used whenever and wherever injuries occur. The single-use design is easy to activate; just snap the bag to open up the chemicals inside for an instant cold reaction. At 5 x 6 the packs are large enough to use over the most commonly affected areas including across knees ankles and shoulders over the lower back and forehead and more. Each box contains 24 instant cool packs.