Here is a compendium of fundamental problem formulations of analog design centering and sizing. It provides a differentiated knowledge about the many tasks of analog design centering and sizing. In particular coverage formulates the worst-case problem. The book stands at the interface between process technology and design technology detailing how the two are required to reach a solution. It presents a mathematically founded description based on numerical optimization and statistics. This volume will enable analog and mixed-signal designers to assess CAD solution methods that are presented to them as well as help developers of analog CAD tools to formulate and develop solution approaches for analog design centering and sizing.