24-Hour Relief: Heartburn happens when stomach acid refluxes into the esophagus, causing uncomfortable heartburn symptoms; when taken as directed, this 24-hour treatment helps to relieve the painful burning sensation of frequent heartburn symptoms #1 Active Ingredient: Omeprazole is the #1 Active Ingredient for Frequent Heartburn (based on iRi sales volume among PPI products sold in the United States, for the 52 weeks ending 01/01/23); compare to Prilosec OTC Frequent Heartburn Relief: For frequent heartburn that occurs two or more days a week, take once every 24 hours for 14 days; this heartburn medicine is not intended for immediate relief of heartburn and may take one to four days for full effect Physician Recommended: Omeprazole is a PPI, the #1 Physician Recommended type of OTC acid reducer (of U.S. physicians surveyed by an independent market research firm); FSA/HSA eligible Wildberry Mint Coated Tablets: PPIs deactivate pumps in the stomach lining to inhibit acid production.