Jarrow Vegan Methyl Folate Extra Strength delivers 400 mcg of stable bioavailable folate in each serving. Methyl folate is the most biologically active form of folic acid. Quatrefolic(R) is the fourth generation development in folate delivery. With certain inherited errors in metabolism and under a variety of physiologic stresses the transformation of folic acid into the active form of folate either does not properly take place or is inadequate. This form of folate can cross the blood-brain barrier. Methyl Folate is needed to support cardiovascular and neurological health and proper cell division. No wheat gluten soybeans dairy egg fish/shellfish peanuts/tree nuts or sesame.