In this two-player cooperative action-adventure game, a sudden crime wave has hit the city, calling Megamind into action. As Megamind, players must defend the city after his untested and unstable inventions are stolen by a group of new enemies called "The Doom Syndicate". To defeat these vile villains, players will have to operate a variety of Mega-Gadgets, including Tesla Gloves, the Battlesuit and Sticky Boots, as well as build ingenious inventions such as the Mega Essence Tracker and the Bio Essence Neutralizer. The game also offers six side mission mini-games and cooperative play with one of Megamind's trusty Brainbots.