PPI for Reducing Stomach Acid and Frequent Heartburn Nexium 24HR Acid Reducer Heartburn Relief Capsules with Esomeprazole Magnesium block acid directly at the source to provide complete relief from frequent heartburn no matter what triggers it. Just one easy to swallow Nexium 24HR heartburn relief capsule a day provides complete all day, all night protection from heartburn (1). Part of a group of medications called proton pump inhibitors (PPIs), Nexium 24HR capsules contain a delayed release formula with esomeprazole magnesium, a stomach acid reducer, to block acid at the source, turning your body’s acid pumps from on to off for complete heartburn protection (2). Like other PPIs, Nexium 24HR acid blocker capsules may take from 1 to 4 days to reach full effect, but relief lasts for 24 hours, letting you power through your day and sleep peacefully through the night without heartburn interruptions. This package of Nexium 24HR capsules contains a 14-day course of treatment in one convenient box. Don't let heartburn pause the moment. Stop acid before it starts with Nexium 24HR. (1) Use as directed for 14 days to treat frequent heartburn. Nexium 24HR may take 1 to 4 days for full effect. (2) It's possible while taking Nexium 24HR. Use as directed for 14 days to treat frequent heartburn. Do not take for more than 14 days or more often than every 4 months unless directed by a doctor. Not for immediate relief.