Advanced Research Zinc Orotate 9.5 mg. - 100 Tablets Zinc orotate is a mineral transporter where zinc is bound to orotic acid, a natural component of whey. Zinc orotate, according to Dr. Nieper, is a nutrient officially on the market in Germany used by doctors to help overcome immune fatigue. Zinc orotate when ingested orally as a mineral supplement can support immune function by activating the thymus gland when a person has zinc deficiency.