Eddie Murphy stars as Dr. Sherman Klump a kind calorically challenged genetics professor who longs to shed his 400-pound frame in order to win the heart of beautiful Jada Pinkett. So with one swig of his experimental fat-reducing serum Sherman becomes Buddy Love a fast-talking pumped-up plumped-down Don Juan. Can Sherman stop his buff alter ego before it s too late or will Buddy have the last laugh.