Nature Made SAM-e Complete is from America s number one supplement brand so when it comes to natural support for a positive mood and mental outlook it s a name you can trust. So is SAM-e a unique nutrient with studies showing its positive potential for both mood and joint health. SAM-e is a naturally occurring molecule produced by your body and it helps maintain healthy emotions. But your SAM-e levels can run low due to various factors such as diet and aging. Replenish your natural levels with Nature Made SAM-e Complete proven to restore a healthy mood in as little as 7-14 days when taken daily.